Nexxus

December 3, 2010

Openness and knowledge-sharing

Filed under: Uncategorized — nexxuscol @ 4:46 pm

I had a couple of days in Manchester last week at the 7th annual BioprocessUK meeting. This is a meeting that I’ve enjoyed in previous years when I worked for a biotech bioprocess business, and which has always focused on what it’s title suggests. It has always been a really good meeting, and this year, after a 3 year gap, I noticed an increased sense of community among all attendees – it felt inclusive with real openness in presentations and networking between colleagues from different businesses. I know that that is testament to the work the Healthtech & Medicines KTN staff does outwith the meeting through Special Interest Groups, and with the Bioprocessing Research Industry Club, as well as directly with its community members. It’s a Nexxus ambition to help create that same feeling of open community between Nexxus network members, especially as you ought to be able to benefit from it.

The image alongside is a ‘wordle’ of keywords folk have submitted when registering for Nexxus events in Edinburgh over the past 18 months. The keywords usually sit alongside individual names on event attendee lists, so the ‘wordle’ is a never-seen-before compilation of keywords from multiple events and shows some of what you have in common  – medical, research, development – and, if you look closely – some of the specialisms you each have. I suspect you won’t be able to read the specialisms, but Nexxus has the searchable list, and the point is a reminder that the Nexxus staff can use the list to help direct you to your colleagues in the network who have the specialist knowledge to help your work.  If you want to use the network, and/or add your specialist knowledge for others to use, get in touch and let Nexxus know.

Nexxus Life Science Awards 2010

Filed under: Uncategorized — katefnexxus @ 3:33 pm

We’ve now held both our East and West Life Science awards for 2010 and though this post is a little late in getting out there – we’d like to once again congratulate all of our nominees and winners. We all had a wonderful time – and hope you did too – at our 2010 awards events at Oran Mor in Glasgow and at the Playfair Library in Edinburgh.

Nexxus Life Science Award Winners (West)

Our winners this year in the west are (from left): Kevin Moore of Business Therapies winner of the Lifetime Achievement Award; Dr Fiona Henriquez of the University of West of Scotland winner of the Young Life Scientist of the Year Award, Chris Hillier of Sistemic the Most Promising Young Life Science Company of the Year, Dr Mike Mattey of FixedPhage, winner of the Innovation Award.

 

Nexxus Life Science Award Winners (East)

And in the East: Nexxus Life Science Award winners  (above in the Playfair Library) are (from left): John Mackinlay of Solid Form Solutions, the Most Promising Young Company of the Year; Professors Ken and Noreen Murray, winners of the Lifetime Achievement Award; Dr Ben Panter of Blackford Analysis, winner of both the Innovation Award and the Collaboration Award (the latter sponsored by Edinburgh Science Triangle); and Dr Asier Unciti-Broceta of the University of Edinburgh, winner of the Young Life Scientist of the Year Award.

Congratulations to all, and if you were at the awards, let us know what you liked (or didn’t like!) about the events and we’ll work on making them even better next year!

 

November 19, 2010

Live forever?

Filed under: Uncategorized — graemeboyle @ 12:52 pm

‘If you have an apple and I have an apple and we exchange these apples then you and I will still each have one apple. But if you have an idea and I have an idea and we exchange these ideas, then each of us will have two ideas.’ George Bernard Shaw

Well this has definitely been a couple of weeks in which ideas have been shared and big issues debated.

The Nexxus Awards nights were fantastic due both to the outstanding achievements of the short list and winners and to the support from you the Nexxus community – thank you once again.

Nexxus also hosted the LiSAB Strategy Review meetings in Glasgow and Edinburgh and a couple of issues stood out for me:

(1) The weaker GVA performance of the life science cluster relative to other sectors – are we measuring the correct things or things correctly? We have a task on hand to ensure that the government and public understand just how much bioscience contributes to the wealth and the health agendas.

What brought this home to me was a late night conversation with a black cab driver on the way back from an Nexxus event. ‘Whit dae ye dae?’ asked the driver.

To which I replied ‘I work with life science companies and researchers’

‘Whit’s life sciences…is that like doctors ‘n ‘hospitals?’ ‘A bit’ said I

‘ Tell me big man (sic) why can ye no live forever?’.

At that I did a Ronnie Corbett and we headed of a wiki-lite review of HeLa cells. The taxis then draws up outside my house. ‘That wiz brilliant…I didnae know anything aboot a’ that – might be useful if am oan Millionaire’.

That brought it home… most people are interested in what life science researchers and companies do – it’s just that no-one tells them about it or, equally importantly, listens to what they want to hear.

A part solution – life science stand-up! UCL does this in London where comics and researchers (perhaps one and the same) share the stage and their passions with a (paying) audience see www.brightclub.org …its just a thought  but it might work here?

(2) collaboration between companies doesn’t happen – and should and can. This is something that Chris Hillier of Sistemic is passionate about. Is there some way we could develop genuinely co-operative models of product development where we pool resources and expertise?

October 26, 2010

UK and Life Sciences R&D

Filed under: Uncategorized — graemeboyle @ 8:31 am

I had the good fortune to attend the BIA/ABPI conference on the UK as a centre for life sciences R&D. The presentations were excellent and formed and interesting companiion piece to last night’s Horizon programme on the value still to be realised from the human genome project.

David Willetts, MoS Universities & Sciencesl, announced the lauch of the first 2 therapeutic capability clusters – these are focusing on immunology and inflammatory joint and respiratory disease. The clusters are built upon the principal of intergrating HEI, Industry and NHS R&D – something that the Nexxus community will be very aware of. The challenge is that Scotland is not represented (due to devolution of NHS funding). We need to ensure that the Scottish research community also plays it part, perhaps indirectly.

For me the most illumintating and inspirational presentation came from Professor Sir John Bell – President of the Academy of Medical Sciences. He layed down the challenge of how to develop a new model of funding that recognises that bridges the gap between fundamental and pre-clinical R&D.

I sign off for just now but will provide some more feedback soon.

October 13, 2010

And the winner is……

Filed under: Uncategorized — nexxusjc @ 12:07 pm

October is an exciting (and busy) time at Nexxus as it’s the month when those who’ve been shortlisted for our Annual Nexxus Awards are sending in additional information for consideration by our judging panel, and the judges subsequently send in their choices of winners across the various categories.

This year is the sixth year of the Awards in the West and the second in the East and I can still remember the trepidation with which we approached the first Awards.  Would anyone enter?  Would anyone come to the Awards evening (the first was in the City Chambers in Glasgow) to help us celebrate the richness and accomplishments of the local life science community?  Well, year on year the number of entries has built and the Awards evening has become one of the “must attend” events in the local life science calendar so it seems we needn’t have worried (but trying something different is always a bit nerve racking!).   This year the Awards events promise to be among the best yet as we have two very influential – and inspirational – ladies giving the keynote speeches – Harriet Fear, CEO of One Nucleus Ltd at the West Awards on 10 November in Glasgow  and Anne Glover, Chief Scientific Adviser for Scotland at the East Awards on 16 November in Edinburgh.   Not to mention the excitement of having the chance to see this year’s entries for our Life-Sci Visions Calendar (there’s still time to get your entry in by the deadline of 22 October).

The only negative aspect about the Awards from my point of view (and no doubt from Kate’s over in Roslin too) is that not all of the entrants for the Awards can be shortlisted, and not all of the shortlisted candidates can be winners.   If only they could all win a Nexxus Award – because in my books they all deserve one!  

But don’t be despondent if you didn’t make the shortlist or you’re not one of our Award winners, there are other Awards you can enter including :-

the SE Annual Life Science Awards - closing date 29 October 2010.

or, if you’re an SME, EuropaBio’s Most Innovative European Biotech SME Award 2010 - closing date 9 November 2010.

Nothing ventured, nothing gained…………… Good luck!

October 1, 2010

Delayed thoughts from the YCF conference

Filed under: Uncategorized — osiannexxus @ 3:55 pm

In a delayed reaction to the Young Companies Finance conference I came away with a couple of thoughts.

Firstly, there was an often raised issue that it is impossible to be a lean start-up in the life sciences, that the whole technology driven principle for product/service development is unavoidably costly. I do wonder if there are examples of lean life science start-ups in Scotland (or further afield), or if this can be applied to any particular segment of the industry? Perhaps it is the virtual value-add services that can fit into this category; no premises, little equipment and development or IP costs to increase the burn rate? With some creative thinking others have tried to offset expensive development by generating an income as soon as possible. Pharmacells is an interesting model, their Oricells product for harvesting and storing Blastomere-like Stem Cells from peripheral blood is designed for early income generation and will subsequently fund the more costly research and development of these cells being launched as commercially available non-embryonic derived pluripotent adult stem cell line designed to come online at a later stage. What can also help lower the burn rate, or simply increase the company value is engagement with the Universities and other publically funded bodies to tap into their resources. There are several schemes and mechanisms to fund engagement, used creatively this can be applied in a variety of ways to help a company in the production of an iPhone app, gain market intelligence, produce engineering solutions (not an exhaustive list by any means) or the more conventional life science knowledge exchange. It is all there, however, with public funding cuts imminent who can say for how long.

Secondly, the YCF conference had an emerging ventures section and I was pleased to see that life sciences related ideas dominated this section – all at the very bleeding edge of their fields and offering real benefits over current technologies. While Jonathan Harris of YCF maintains that this cross-section is more due to luck than judgment, if it can be considered a snapshot of the young company landscape in Scotland then surely  it is testament that Scottish life science entrepreneurs are still out there. If these entrepreneurs, and others like them, found the financial backing required this would be very good news indeed. I did note that the majority looked to be very expensive technologies to develop!

September 25, 2010

Outreach

Filed under: Uncategorized — katefnexxus @ 10:30 am

A programme about Richard Feynman was on Radio 4 last weekend, and in listening to it, one was amazed all over again at his genius and his incredible enthusiasm for science that came through in the excerpts from interviews and speeches .

His genius is clear, from his youth spent repairing radios to his involvement in The Manhattan Project at Los Alamos as a young physicist working on the development of the atomic bomb (and picking the locks of safes in his spare time). Later in his career, he made significant contributions to quantum mechanics, particle physics, won the Nobel Prize in Physics, wrote amazingly popular books about physics, and maintained a voracious appetite for learning. In addition to physics, he was very interested in the life sciences – biology, genetics, microbiology. His famous ‘There’s Plenty of Room at the Bottom’ speech in 1959 paved the way for the fields of nano-science & nanotechnology.

While his intelligence is clear from his achievements, his insatiable curiosity and desire to learn about the world around him were also cultivated by his father. Feynman said that when he was a child, his father would read aloud to him from the Encyclopaedia – he would read something like (I’m paraphrasing here) “The Tyrannosaurus rex was 20 feet tall and its head was 6 feet wide.” And then, Feynman’s dad would stop reading and get out a tape measure and say, “Wait what does that mean? It means the T. Rex could reach up as high as your bedroom window, but it couldn’t get its head through the window because it would be a little bit too wide.”  He put everything they read into real-world terms.

This is the type of curiosity and enthusiasm for scientific disciplines that many teachers, communities, universities, and national governments attempt to instil in students today.  There is much concern over whether we are bringing up, educating and recruiting enough young people into the STEM disciplines, and outreach has become a big part of scientific endeavour. It is a built-in component of most government science grants in the US.  An incredible variety of programmes exist to get kids interested in science. Science-related companies get involved too because a company is only as good as the skilled workforce available, from which they can hire their next generation of great scientists.

It’s an interesting area and no one has the magic key to what works best yet, but in March of this year the Higher Education Funding Council (for England) published a report with some positive news:  6.8% more students are studying subjects such as physics, chemistry and math than in 2005-06. Hopefully, we’ll see these trends continue. More on the report here. However, with the threat of significant cuts to science funding looming, one wonders (gloomily), if investing in training the next generation of scientists will simply result in their departure for greener scientific pastures

In any case, here’s an example of the positive outreach efforts of one local company:

In addition to having several Modern Apprentices working in their labs, Ingenza gets out in the community to “raise science awareness amongst the local community.” Read more about it here.

For those of you who are thinking about a science career, or already in the sciences but looking to try out another aspect of the field, we have our Nexxus Career Paths in Life Science event coming up soon on 7 October.

What does your comapny do to reach out to prospective young scientists or the community at large? Why do you see this as valuable?

September 17, 2010

To VC or not to CV

Filed under: Uncategorized — graemeboyle @ 12:24 pm

Earlier this week I had the pleasure in attending the first Wellcome Foundation European networking event at the Gibbs Building in London.

It was great to see how Scottish companies such as Cardioprecision Ltd, Roslin Cells, The Scottish National Blood transfusion Service and The Drug Discovery Unit at the University of Dundee are using translation funding to develop best-in-class technology that is both to the benefit of the patient and potentially the basis of new enterprises.

There was an excellent turnout of Euro VC’s and other funders. There was common agreement that exits are almost non-existent at the moment but that this time represented a good time to acquire technology/IP. Talk also turned to the importance of angel investment – with the consensus being that this is something the UK does well (especially in Scotland I would add).

But no matter what the old saw of the funding gap was debated. The feeling was that the time had come for the re-emergence of Corporate Venturing (CV). This was in part a strategy to fill big Pharma’s pipeline but it also followed the trend for open innovation and collaboration between SMEs and Big Bio/Pharma.

On returning to Scotland I had the opportunity to visit the GSK site in Irvine along with other members of the Glasgow City of Science Steering Group. The tour of the site was an eye-opener – it is one of the largest users of power and water in Scotland and its products compete with the low-cost economies of China and India. The teams of engineers and technologists are all engaged in continuous improvement programmes/Kaizen and are constantly striving to reduce costs, maximise efficiency and minimise environmental impact. Taking amoxil/augmentin will never be the same again!

Reflecting back on this is highlights the reach of life science – producing ‘weightless’ ideas through to metric tonne level of chemical compounds – but both relying on innovation and collaboration.

September 10, 2010

Causal Nexxus?

Filed under: Uncategorized — nexxuscol @ 4:21 pm

A lot of good presentations, and insight to excellent research collaborations at the Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE ) Annual Research Day earlier this week. Plenty to get me thinking – and doing my bit to mitigate cognitive ageing -so just a couple of thoughts to share here.
CCACE is working with artists as part of its projects. Garry Hunter spoke about his planned work with CCACE, and mentioned that he’s ‘given-up’ with digital photography as the image is captured and over in an instant: it doesn’t cause the artist or the viewer to pause and consider.
Nancy Pedersen from the Karolinska Institute spoke about “the changing role of genes in cognitive ageing,” and introduced me to GxE – genome by environment. This is the reality that there is “an ever-changing causal nexus” bringing longitudinal changes to the array of complex interactions between gene products/the genome.
So, on the one hand we all the tools we need for instant capture and transmission of information and that fits with our modern, fast-paced lifestyle – when was the last time you met someone who didn’t say they were busy or hectic? And, on the other, recognition that the little things that happen on a daily basis link together and become, on review, the series of events that lead to an outcome – in Professor Pedersen’s examples, earlier onset of ‘cognitive ageing.’
So what of Nexxus – with double x? Well, you can use Nexxus to grab a quick look at some of the life sciences activity in Edinburgh and Glasgow. Close to 4.000 others do this each month on www.nexxusscotland.com. And, you can make a link in your causal nexus by talking through Nexxus – at events, to the staff, to your peers – and make a link that might prove to be a key one in your future success. It’s only by looking backwards that you’ll see what the key links were, so use Nexxus to make some links today.
Lastly, Professor Ian Deary, Director of CCACE is speaking at the Nexxus Horizons in Ageing event in Edinburgh on 28th October. As well as being a very talented researcher, Ian is an engaging speaker, and it will be good to welcome you along, to let you hear about some of the exciting research at CCACE -and across the community -, and to make links to others interested in opportunities around the ageing grand challenge.

July 30, 2010

The day is darkest…just before the dawn- 30 July 2010

Filed under: Uncategorized — graemeboyle @ 12:32 pm

Many of you will have missed this…but at 0530hrs this morning the East End of Glasgow was veiled by a Turner-esque sky framed by  a magnificent double rainbow. Not only that but my buddies the brace of  inner-city Roe Deer also made an appearance. It made running along the Clyde Pathway an absolute joy…and it got me thinking (running usually does)…how can the same elements that combine to provide this outstanding summer spectacle also give us the dubious pleasures of the dark grey maudlin skies of a Scottish January.

I know this may come across as a bit Polly Anna-ish but perhaps its an analogy for the times in which we live – the economic pressures that are driving job losses, cut-backs and retrenchment might, just might, possibly give rise to new life-affirming opportunities. ‘Hey!’ I can see some of you thinking ‘Mr B has lost all grasp of reality’  but maybe that’s what we all need to do once in a while…

East End Sky 300710

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